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KMID : 1004520140300040299
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Journal of Dental Rehabilitation and Applied Science
2014 Volume.30 No. 4 p.299 ~ p.306
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The prevention of mortality after botulinum toxin injection in oral maxillofacial region
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Lee Won-Kang
Choi Young-Chan
Choi Moon-Jong
Kim Seong-Taek
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Abstract
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Botulinum toxin (BoNT) has been used for a wide spectrum of therapeutic and cosmetic indications, and the range of indications is continually increased. Though BoNT is a powerful poison, the fact that not only the effect but also the adverse effect of it fader about 6 months after injection makes clinicians to neglect its dangerous property in clinical application. But Many reports about the adverse effects including death of BoNT injection have been reported, the FDA edited in additional warnings about hospitalizations and deaths. In this study, we intended to look through the metabolic process in human body, possible adverse effect, matters to be attended in application, and cases reports about deaths of BoNT by reviewing the previous studies.
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KEYWORD
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botulinum toxin, metabolic process, adverse effects, death
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